Indiana’s newly developed social-emotional learning (SEL) competencies for students in grades Pre-K through 12, were designed to address social and emotional well-being through a neurodevelopmental culturally responsive framework. The foundation for these competencies has been developed from the most current brain research, social-emotional research, and trauma and culturally responsive best practices. The new SEL competencies build upon CASEL’s five core Social-Emotional Learning Competencies by adding competencies that address mindset and sensory-motor integration addressing the brain stem, limbic system and cortical functions of a child and adolescent’s brain development.